Scientists have claimed that there are six different "types" of COVID-19, each with a different set of symptoms in patients. If the results are validated, they can help doctors better diagnose and monitor people infected with the novel coronavirus.
The pending peer review study published on the medRxiv preprint platform used a machine learning algorithm to gather data from a subset of around 1,600 users in the UK and US with confirmed cases of COVID-19 Analyze their regularly logged symptoms using the app in March and April.
It was analyzed whether certain symptoms appeared together and how this is related to the progression of the disease.
According to scientists led by King & # 39; s College London in the UK, the results have a significant impact on the clinical management of COVID-19 patients.
"These results have important implications for the care and surveillance of people most susceptible to severe COVID-19," said Claire Steves, co-author of the study from King’s College London.
They said research can also help doctors predict who is most at risk and likely to need hospital care in a second wave of coronavirus infections.
The study found that the patient's symptoms could fall into one of six categories: "flu-like" without fever, "flu-like" with fever, gastrointestinal tract, severe stage one with fatigue, severe stage two with confusion and severe level three accompanied by abdominal and breathing pain.
In the first category of patients who reported “flu-like” symptoms without fever, the scientists said the manifestations included odor loss, muscle pain, cough, sore throat, chest pain, but no fever.
According to their analysis, those in the second category had headache, loss of smell, cough, sore throat, hoarseness, fever, and anorexia, and those in the gastrointestinal symptoms group had a combination of headache, loss of smell, loss of appetite, diarrhea, sore throat, but chest pain no cough.
In the "Severe Level One with Fatigue" category, the scientists reported that patients reported odor loss, cough, headache, fever, hoarseness, chest pain, and fatigue, and those with severity level two expressed the same symptoms with the addition of anorexia, sore throat, Confusion and muscle pain.
In the most severe category, the study found that patients had headache, loss of smell, loss of appetite, cough, fever, hoarseness, sore throat, chest pain, fatigue, confusion, muscle pain, shortness of breath, diarrhea and abdominal pain.
According to the study, everyone who reported symptoms had headache and loss of smell, with different combinations of additional symptoms occurring at different times.
It is said that some of the manifestations, such as confusion, abdominal pain and shortness of breath, are not commonly known as COVID-19 symptoms, but are hallmarks of the most severe forms of the disease.
The scientists also analyzed whether people with certain symptom clusters were more likely to need breathing support in the form of ventilation or additional oxygen.
According to the study, almost half of the patients in cluster 6 ended up in the hospital, compared to only 16 percent of the patients in cluster one.
People with symptoms of cluster four, five, or six tended to be older and more frail and more overweight, the scientists said, adding that these patients had pre-existing conditions, such as diabetes or lung disease, than the other types.